Esketamine (Spravato®) Nasal Spray Therapy

When Antidepressants Aren’t Enough, SPRAVATO® Offers a New Path Forward

Esketamine (Spravato®) nasal spray is a breakthrough treatment for adults with treatment-resistant depression and major depressive disorder with suicidal thoughts. FDA-approved and administered in a safe, supervised setting, it offers fast relief when traditional medications fall short. 

Spravato®: A Breakthrough in Depression Treatment

 

Esketamine nasal spray (Spravato®) is a fast-acting option for adults living with treatment-resistant depression. 

FDA-approved and administered under clinical supervision, this breakthrough therapy offers relief when traditional antidepressants haven’t worked. If you’ve tried two or more medications without success, esketamine treatment may offer a new way forward.

Delivered through a nasal spray in a monitored setting, esketamine therapy works by targeting glutamate, an important brain chemical linked to mood regulation. Most patients begin to feel the benefits within hours or days, not weeks.

Still wondering what is esketamine? It’s a safe, medically guided treatment that’s different from typical antidepressants because it works fast, acts on new pathways in the brain, and is designed for people who haven’t responded to standard care.

What We Offer

Esketamine is a carefully managed treatment experience. We provide a calm, clinical setting where every detail is designed to support your safety, comfort, and progress.

If you’re looking for a new approach to depression that’s backed by science and guided by professionals, esketamine nasal spray could be the solution.

Monitored Sessions

Each esketamine nasal spray dose is given under supervision, with your  well-being carefully observed throughout the visit.

Flexible Scheduling

We adjust the frequency of your treatments based on your response, making sure you get the right support at the right time.

Spravato® Expertise

Our team follows FDA guidelines for esketamine treatment, ensuring each session meets the highest standards for safety.

Maintenance Transition

We guide you through the initial phase and ongoing maintenance sessions to help sustain long-term improvement.

Mind-Body Support

We help you manage both the emotional and physical aspects of treatment-resistant depression.

Respectful Care

Our environment is designed to help you feel safe, supported and in control throughout your treatment journey.

Commonly Treated Disorders

Major Depressive Disorder (MDD) with inadequate response to at least two antidepressants 

Major Depression with acute suicidal ideation or behavior 

Persistent feelings of hopelessness or emotional numbness 

Severe mood disturbances that haven’t improved with traditional medications 

Care That’s Covered and Accessible

We accept major insurance providers, offer out-of-network support, and provide payment plans for uninsured patients.

Take the First Step Toward Relief  

If you’ve tried multiple antidepressants without meaningful improvement or are struggling with suicidal thoughts, Spravato® may offer the breakthrough you need.  

Spravato® is FDA-approved for adults with treatment-resistant depression and for those experiencing major depressive disorder (MDD) with suicidal thoughts or behaviors. It’s used in combination with an oral antidepressant when other treatments haven’t worked.  

Unlike most antidepressants that affect serotonin or dopamine, Spravato® targets the brain’s glutamate system. It helps “reset” how the brain responds to mood and stress by strengthening connections between brain cells. This is why many patients feel relief faster often within the first few doses.  

Spravato® is a nasal spray form of esketamine (a type of ketamine), and it’s FDA-approved and covered by many insurance plans. Ketamine infusions are given through an IV and are typically not covered by insurance. Both are effective for treatment-resistant depression, but the method of delivery and insurance coverage differ.  

You’ll self-administer the nasal spray in our clinic under medical supervision. After dosing, you’ll rest for about two hours in a private room while we monitor your blood pressure and how you’re feeling. You may feel sleepy, dizzy, or detached, this is normal and usually fades quickly.  

No. Due to possible short-term side effects like drowsiness or dissociation, you won’t be allowed to drive after treatment. Please arrange for someone to take you home after each session.  

Spravato® is typically given twice a week for the first month, then once a week, and eventually once every two weeks for maintenance. We’ll tailor the schedule based on how you respond to treatment.  

Yes, when administered in a clinical setting. It’s FDA-approved and has been safely used by thousands of patients across the U.S. You’ll be closely monitored before, during, and after each session to ensure your safety.  

Spravato® may not be right for you if you have uncontrolled high blood pressure, vascular conditions like aneurysms, a history of brain bleeding, or if you’re pregnant or breastfeeding. We’ll do a thorough screening to make sure it’s safe before beginning treatment.